Date of Award
MS Experimental Psychology
Michael Vigorito, Ph.D
Amy Hunter, Ph.D
Jeffrey Levy, Ph.D
Successive negative contrast, Anticipatory negative contrast, self-medication hypothesis, ethanol
According to the self-medication hypothesis, individuals may consume drugs or alcohol, or engage in other behaviors in order to reduce a negative emotional state (Khantzian, 1985; Gross, 2013; Crum et al., 2013). Rats experiencing a negative state induced by various stressors (Bertholomey et al., 2010), or a decrease or loss in reward value of a sucrose solution (Manzo et al., 2015; Manzo et al., 2014) demonstrate increased consumption of alcohol. I used successive (SNC) and anticipatory negative contrast (ANC) procedures to further examine this hypothesis and the previous findings (Manzo et al., 2015), that rats increase consumption and preference for ethanol in post-shift sessions of a SNC procedure. The results of the present study confirm these findings, and in addition, demonstrate that an ANC procedure does not affect ethanol consumption.
Dieterich, Andrew, "Do Rats Consume Ethanol to Regulate a Negative Emotion Induced by a Successive Negative Contrast Procedure?" (2016). Seton Hall University Dissertations and Theses (ETDs). 2155.