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Theses/Dissertations from 2023

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Effect of Copper II Chloride on Proinflammatory Pathway Cytokine Expression and ROS/RNS Production in ATDC5 Chondrocytes, Nicolas Ebner

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Role of fatty acid transport proteins in fatty acid uptake in Neuro-2a cells, Michelle Kim

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Involvement of TRPM7 in Alcohol-Induced Damage of the Blood-Brain Barrier in the Presence of HIV Viral Proteins, Michelle L. Mack

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Molluscum Contagiosum Virus MC160 Protein: A Novel Antagonist of the Cellular cGAS/STING dsDNA Sensing Pathway, Brian T. Reiss

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Book of Abstracts, Seton Hall University

Theses/Dissertations from 2022

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Investigation of the Effect of Trace Element, Copper Chloride, on Chondrogenic Cell Line, ATDC5 Function, Alexandra Bambrick

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Bis-Indolyl Compounds and the Induction of Apoptosis in T98G Glioblastoma Multiforme Cells, Margot C. Brown

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Migrant and Refugee Center: Demographic Collection for Strategic Outreach, Russell Cook

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Migrant and Refugee Center: Health Demographic Collection for Strategic Outreach, Russell Cook

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Molluscum Contagiosum Viral Protein MC159 Interferes with Necroptosis Signaling Downstream of P-MLKL in HEK 293T and HT-29 Cells, Matthew Gregory

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Drosophila Melanogaster as a Model for Male Reproductive System Ethanol Toxicity, Gbemisola Ilelaboye

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An Investigation of the Effects of Insulin and Magnesium on Bone Homeostasis in a 3D Bone Model, Katherine Lefferts

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Creation of Severe Acute Respiratory Syndrome- Coronavirus-2 Spike (AA 14Q-685R) --Fc Fusion Protein, Lea Marjana

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Antibacterial, Anti-Spore, and Antibiofilm Effects of Theaflavin-3,3’-Digallate, Siti Ayuni B Mohamed Yussof

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The Role of DHA in the Impact of TREM2 on Microglia Activation and Alzheimer’s Disease, Michael A. Palmieri III

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Effects of Sodium Orthovanadate on LPS-Induced Senescent RAW 264.7 Cells, Andrew Pugliese

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Investigation of Zinc Chloride & Caffeine and Their ECTS on Bone Homeostasis in a 3D Bone Model, Pooja Shah

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Manganese Chloride Effects Chondrogenesis of ATDC5 Cells, Isabella Somera

Theses/Dissertations from 2021

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The Effects of Ozone Therapy on Fertility in Women with Diminished Ovarian Reserve Undergoing Assisted Reproductive Technology, Ashini R. Dias

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Clinically Relevant Dosage of Vancomycin Does Not Negatively Impact Periosteum Derived Osteoblast Precursor Cellular Functions, Alexis Hernandez

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The Effect of EGCG-P Containing Formulations on Bacillus spp., Sabrina A. Lopez

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Evaluation of Nickel Stress on Anabaena cylindrica, Danielle L. Maragh

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Effects of Palmitate on the Expression of Inflammatory Cytokines in Microglial Cells, Shiyu Ma

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Investigation of RACK1 effect on MOR Expression Using CRISPR Technology, Zil Modi

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Creation of Recombinant Mouse Hepatitis Virus-A59 Spike (AA 1-730) ― Fc Fusion Protein, Lorena Pena

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BioSymposium Book of Abstracts, Seton Hall University

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Molecular Mechanisms of Palmitate Lipotoxicity and Unsaturated Fatty Acid Lipoprotection in Neuronal and Microglial Cells, C.J. Urso

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Antibacterial Activity of Pogostemon cablin, Elizabeth Wong

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The Effects of Chronic Ethanol Exposure on Caenorhabditis elegans Germline, Andrea Zegarra

Theses/Dissertations from 2020

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Effects of Aurora Kinase C Expression on Retina Pigmented Epithelial Cell Migration, Proliferation, and Anchorage Independent Growth, Justin Bejar

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Developing a Yeast Two-Hybrid System to Study Molluscum Contagiosum Virus Protein-Protein Interactions with Human Proteins, Eric Bryan

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CD11b+ Depletion of Bone Marrow Derived Macrophages Negatively Affects Bone Fracture Healing, Sarah Hozain

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Generation and Characterization of a RACK1 Knockout Cell Line, Roy Missall

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Cancer-Targeting Immunostimulatory Peptides as an Immunotherapeutic Approach to Cancer, Rachel Montel

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Effect of Zinc on Microcystis Aeruginosa and its Toxin Production, Jose L. Perez

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The Molluscum Contagiosum Virus targets host innate immune signaling networks at multiple points using viral proteins MC160 and MC163, Catherine D. Suarez

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A Functional Three-Dimensional Microphysiological Model of Myeloma Bone Disease, Richard Visconti

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Isotype-specific outcomes in Fc gamma receptor targeting of PspA using fusion proteins as a vaccination strategy against Streptococcus pneumoniae infection, Kari Wiedinger

Theses/Dissertations from 2019

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Comparison of Nickel and Cobalt Induced Hypoxic Cell Models using Cell Proliferation Assay, Melissa DelCasale

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Characterization of Immune Evasion Properties of the Molluscum Contagiosum Virus MC163 Protein, William De Martini

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Effects of Treatment on Melanoma with Checkpoint Inhibitor, Pembrolizumab (Keytruda ®), Anti-CD47 TTI-621 (Trillium), and Anti-SEMA4D Pepinemab Combination Treatment, Lauren E. Fitzgerald

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Analysis of Post-Translational Modifications and Expression of STAT3 under Desferrioxamine Induced Hypoxia in Human Neuroblastoma Cells, Veronica Harrison

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Analysis of Sublethal Toxicity in Developing Zebrafish Embryos Exposed to a Range of Petroleum Substances using BE-SPME and Whole Transcriptome Microarray, Bryan Matthew Hedgpeth

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Detection, Identification, and Metagenomic Characterization of Cyanobacteria in Barnegat Bay, New Jersey, Roksana M. Rahman

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Zinc Chloride Enhanced Chondrogenesis is VEGF Dependent, Gilbert M. Sharp IV

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Vanadium Compounds Modulate Osteoblast Proliferation and Function, Bryan Sosa

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5 Lipoxygenase's Role in Chondrogenesis of the ATDC5 Cell Line, Tien My Tran

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Molecular Assay Optimization for Enhanced Detection of Legionella spp. in Passaic County, New Jersey, Paul Yoon

Theses/Dissertations from 2018

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Hydraulic Fracturing Fluid Biocide, Tributyl Tetradecyl Phosphonium Chloride, Causes Mitochondrial Dysfunction that is Enhanced by Sodium Chloride in Chironomus Riparius, Zainab Hussain Alali

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The Molluscum Contagiosum Virus MC160 Protein Requires Both Death Effector Domains to Inhibit MAVS- and TBK1-Induced Interferon Activation, Lissette Bouza

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Correlation of Environmental Exposure to Polycyclic Aromatic Hydrocarbons and Polymorphisms in the Proto-oncogene v-Rel using Wild Atlantic Menhaden, Chelsea Rose DeFelice

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Characterization of the Protective Role of Th17 Cells in an Fc Receptor-Targeted Vaccine Strategy Against Fracisella tularensis Infection, Kyle Devenney

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Association of p53 Polymorphisms, PAH-like Fluorescence, and Developmental Trends in Caught Gulf Menhaden to Crude Oil Exposure Post-Deepwater Horizon Oil Spill: A Holistic Approach, Kevin Luiz Frisina

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Development of a Reliable Method to Express and Purify Vaccinia Virus Transcription Factors A7 and D6 in Bacteria, Younghoon Park

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A Study of Exposure to Polycyclic Aromatic Hydrocarbons and Polymorphisms in the Tumor Suppressor Gene, p53, of Wild Menhaden, Samantha Rose Reed

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The Rational Design, Synthesis, Characterization, and Biological Evaluation of Cancer-Targeting Immunostimulatory Peptide-Protein Conjugates and Tripeptides, Keith Smith

Theses/Dissertations from 2017

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Comparative Evaluation of the Antibacterial, Anti-biofilm and Anti-spore Effects of Theaflavins and Palmitoyl-EGCG, Gabriella M. Appice

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Zinc Chloride Activates Phospho-Akt and Promotes Chondrocyte Maturation in the ATDC5 Chondrogenic Cell Line, Donya T. Burgess

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Mutational Analysis of the Molluscum Contagiosum Virus MC160 protein, Henri Estanbouli

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Development of a Novel Method to Express and Purify Vaccinia Virus Early Transcription Factors A7 and D6 using Bacteria, Omkar M. Gandbhir

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Examining the Role of HREs on the Regulation of Opioid Receptor Gene Expression in Neuronal Cells undergoing Hypoxic Mimic Condition, Alberto Herrera

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Human Neuroblastoma Adaptation to Cobalt Chloride-Induced Hypoxia, Conor McAuliffe

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The Effects of Palmitate on the Expression of G-protein Coupled Receptors and GLUT Transporters in Neuro2A Cells, Brian Montoya

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Effects of Crude Oil on Tumor Suppressor p53 Polymorphisms in Laboratory-Exposed Atlantic Killifish, Fundulus heteroclitus, Allison Margaret Nadler

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Characterization of Zinc and Cadmium Stress Response in Cyanobacterium Synechococcus sp. IU 625, Robert Newby Jr

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Platelets Prime Hematopoietic-Vascular Niche to Drive Angiocrine-Mediated Liver Regeneration, Koji Shido

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Development of Markers for Embryonic Reproductive Competence in Assisted Reproduction, Xin Tao

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Transcriptome Approach for Identifying Potential Biomarkers for Endocrine Disruption due to Crude Oil Exposure using Killifish (Fundulus Heteroclitus)., Frank J. Zadlock IV

Theses/Dissertations from 2016

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A Bioinformatics Methodology for the Annotation and Analysis of Sperm Chromatin Remodeling Proteins in Sequenced Drosophila Species, Zain A. Alvi

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Apical Testis Structure and the Effects of Cadmium Treatment on Spermatogenesis in Drosophila, Paulina J. Cardaci

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TLR3 Signaling in Human BDCA-3 Dendritic Cells Results in the Formation of Several ILT3 and ILT4 Populations, Nicholas J. Colletti

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Characterization of a Mitochondrial Localizing Molluscum Contagiosum Virus Protein: MC163R, Jesse Coutu

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Modified Green Tea Polyphenol, Palmitoyl-EGCG and Black Tea Theaflavins: Promising Natural Herpes Simplex Virus 1 and 2 Agents, Aline Moraes de Oliveira

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Flow Cytometric Analysis for Cyanobacteria in 36 New Jersey Freshwater Bodies, Ruchit Patel

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Utilization of Cholera Toxin B as an Adjuvant for the Subunit PspA Vaccine, Provides Effective Protection against Streptococcus pneumoniae Challenge, Daniel R. Pinho

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The Effect of Increased Sleep on the Circadian Rhythm of Salivary Cortisol Concentrations, Mariah Jacqueline Scott

Theses/Dissertations from 2015

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Mechanisms Involved in Enhanced Protection Against Gram Negative Bacterium Francisella tularensis Utilizing an FcR Targeted Vaccine Platform, Zulfia Babadjanova

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Antibacterial Evaluation of Polygonum Multiflorum, Andy S. Demianicz

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Testing the efficacy of LSN2463359, a metabotropic glutamate 5 receptor positive allosteric modulator, in animal models of schizophrenia, Dierdre M. Freamon

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Polycyclic Aromatic Hydrocarbon determination in liver of Menhaden exposed to the Deep Water Horizon Oil Spill, Rebecca Hawke

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Effect of Chinese Knotweed Extract on HSV-1 Infection of Vero Cells, Derek J. Prince

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Salivary VIP concentrations are elevated in humans after acute stress, Giovanni Ventre

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Functional Analysis of the Molluscum Contagiosum Virus MC160 Death Effector Domain-Containing Protein RxDL Motif, Sarah Weber

Theses/Dissertations from 2014

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HIV-1 Transgenic Rats Display Alterations in Immunophenotype and Cellular Responses Associated with Aging, Susan J. Abbondanzo

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The Use of Natural Products as Potential Anti-Pseudomonas Agents, Margaret B. Bell

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Effects of DFO-Induced Hypoxia on Key Signaling Mediators, Jennifer Candelora

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Identification and Characterization of Phytoplankton in Barnegat Bay, New Jersey, Nicole L. Elia

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Investigations on the Effects of Palmitate on Neuronal Cells, Ryan Gelsinger

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Molecular Characterization of Hemoglobin Protein in Larvae of 4th Instar Chironomidae for Evaluating Environmental Quality, Jun Taek Oh

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Chemical Induced Hypoxia Differentially Affects Gene Expression in Human Neuronal Cells, Natasha V. Pavlichko

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Detection of PAHs in Commercial and Wild Caught Fish Oil using Scanning Fluorescence Spectroscopy, Edwin Antonio Pena

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Palynological Evidence for the Paleoenvironmental History of the Miocene Llanos Basin, Eastern Colombia, Ingrid Carolina Romero Valero

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Use of Cholera Toxin B as a Vaccine Adjuvant Activates Antigen Presenting Cells and Stimulates Production of Pro-Inflammatory Cytokines, Heather C. Romlein

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Transcriptome Analysis of Sea Lamprey Embryogenesis, Zakary Ilya Yermolenko

Theses/Dissertations from 2013

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RNA interference targeting Glucose-Regulated-Protein 78 induces HepG2 cell Apoptosis, Brittany Blackman

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Fumarate Inhibits TNF-α Release, Megan Kelly

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Identification of the Interaction Between RACK1-PCBP1 and Characterization of the Novel Functional Effect of the Interaction, Pranjal Nahar-Gohad

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The Effects of Nickel Chloride Stress on Freshwater Cyanobacterium Synechococcus SP. IU 625, Brian Nohomovich

Theses/Dissertations from 2012

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Endotoxin-Induced Inflammation & Morphine-Induced Conditioned Place Preference in the HIV-1 Transgenic Rat, Natasha F. Homji-Mishra

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Characterization of the Stem Cell Niche in Drosophila Testes, Vittorio Mena Jr.